Our latest paper with title "Molecular Mechanisms of Macular Degeneration Associated with the Complement Factor H Y402H Mutation", by Reed Harrison and Dimitrios Morikis, is now published online in Biophysical Journal. DOI: https://doi.org/10.1016/j.bpj.2018.12.007. The paper proposes a novel mechanism for the involvement of a major polymorphism of the complement system in age-related macular degeneration. This...

Bioengineering senior and BioMoDeL undergraduate researcher, Jaya Vengadesan, presented a poster of her work at the 2018 Southern California Conferences for Undergraduate Research (SCCUR, https://www.sccur.org/). The title of her poster was "Evasion of Complement System Immune Response by Neisseria Meningitidis, through the Formation of the Factor H – Factor H Binding Protein Complex". Co-authors in...

A new BioMoDeL paper is published in Frontiers in Physics - Biophysics. The citation is: Zewde N, Mohan RR, Morikis D (2018) Immunophysical evaluation of the initiating step in the formation of the membrane attack complex, Frontiers in Physics 6:130 (17 pages). DOI: 10.3389/fphy.2018.00130.

BioMoDeL undergraduate researcher alumnus, Jose Gomez, received his Master of Applied Science degree from the University of Victoria, Canada.

October 2018. Newly minted BioMoDeL PhD, Rohith Mohan, started his new job at Dassault Systèmes BIOVIA, a scientific innovation company in San Diego.

Congratulations to Rohith Mohan for defending successfully his dissertation and receiving his PhD degree. Rohith's dissertation title is: Mapping the Druggability of Complement C3 and its Derivatives, and Inhibitor Design.

http://wang.ucsd.edu/ Newly minted BioMoDeL PhD, Reed Harrison started his postdoctoral fellowship in the group of Peter Wang, Bioengineering, UCSD.

Congratulations to Reed Harrison for defending successfully his dissertation and receiving his PhD degree. Reed's dissertation title is: Multi-Scale Design of Surveillance and Regulation Within the Complement System.

https://pubs.rsc.org/en/content/articlepdf/2018/nr/c8nr03229g Ngo-Duc T-T, Plank JM, Chen G, Harrison RES, Morikis D, Liu H, Haberer ED (2018) M13 bacteriophage spheroids as scaffolds for directed synthesis of spiky gold nanostructures, Nanoscale, View Online. DOI: 10.1039/c8nr03229g.

https://www.nature.com/articles/s41598-018-28214-2?WT.feed_name=subjects_proteolysis Malik-Chaudhry HK, Gaieb Z, Saavedra A, Reyes M, Kung R, Le F, Morikis D, Liao J (2018) Dissecting Distinct Roles of NEDDylation E1 Ligase Heterodimer APPBP1 and UBA3 Reveals Potential Evolution Process for Activation of Ubiquitin-related Pathways, Scientific Reports 8: 10108 (10 pages). DOI: 10.1038/s41598-018-28214-2.

https://bic2018.engr.ucr.edu/ The 19th University of California Systemwide Bioengineering Symposium has come to end, and was a great success! All BioMoDeL graduate students gave oral or poster presentations, and volunteered for various organizational tasks during the conference. Professor Morikis was a member of the organizing committee, and chaired sessions.

https://bic2018.engr.ucr.edu/ BioMoDeL graduate students, Reed Harrison, Rohith Mohan, Nehemiah Zewde, and Rohaine Hsu, presented their work at the 19th UC Systemwide Bioengineering Symposium that took place in Riverside. Another collaborative project was also presented by Professor David Lo's postdoctoral fellow Casey Gries.

https://bic2018.engr.ucr.edu/ BioMoDeL graduate student Reed Harrison received the award for best poster presentation at the computational bioengineering track at the 19th University of California Systemwide Bioengineering Symposium. The symposium was hosted by our department, and was held in Riverside during June 21-21.

https://escholarship.org/uc/item/14z8979k Undergraduate BioMoDeL researcher and Bioengineering junior, Nolan Winicki, has published the paper with title " Identification of Targetable Surfaces of Cks1 for Development of New Cancer Therapeutics" in volume XII of UCR Undergraduate Research Journal. Co-authors in the paper are Reed Harrison, BioMoDeL graduate student, Professor Jefferson Perry of UCR's Department of Biochemistry, and...

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198644 June 2018. Zewde N, Morikis D (2017) A Computational Model for the Evaluation of Complement System Regulation under Homeostasis, Disease, and Drug Intervention, PLOS ONE 13(6): e0198644 (28 pages, 177 pages supplementary information).

https://pubs.acs.org/doi/abs/10.1021/acsomega.8b00606 June 2018. Mohan RR, Wilson M, Gorham RD Jr, Harrison RES, Morikis VA, Kieslich CA, Orr AA, Coley AV, Tamamis P, Morikis D (2018) Virtual screening of chemical compounds for discovery of complement C3 ligands, ACS Omega 3:6427–6438.

https://ssp.ucr.edu/journal/ Undergraduate BioMoDeL student-researchers Siddharth Sai, Jayapriya Vengadesan, and Nolan Winicki served in the Student Editorial Board of Volume XII of the UCR Undergraduate Research Journal.

https://ssp.ucr.edu/symposium/ Undergraduate student-researchers, Nolan Winicki (3d year), Sharon Gupta (4th year), Vivian Luong (4th year), and Siddharth Sai (3d year) presented their research at the UCR Undergraduate Research Symposium that took place in May 7-8, 2018.

http://graduate.ucr.edu/ Rohith Mohan, fifth year graduate student, received the 2017-2018 Best Teaching Assistant Award in Bioengineering by UCR's Graduate Division.

http://graduate.ucr.edu/fin_aid.html Nehemiah Zewde, fourth year graduate student, received a one-quarter Dissertation Year Program (DYP) fellowship award for 2018-2019. Nehemiah is expected to complete his doctoral degree in bioengineering by summer 2019. The DYP award is administered by UCR's Graduate Division.